Altitude
← Encyclopedia

Dextromethorphan (DXM)

Compound

A cough-suppressant ingredient with dissociative, NMDA-antagonist effects at high doses, chemically unrelated to classic psychedelics.

Example: Combined with bupropion, it's the active ingredient in Auvelity, a genuinely novel FDA-approved antidepressant — see its revenue and patent position.

What is dextromethorphan (DXM)?

A cough-suppressant ingredient with dissociative, NMDA-antagonist effects at high doses, chemically unrelated to classic psychedelics.

Is DXM used in any approved psychiatric drug?

Yes — combined with bupropion, it's the active ingredient in Auvelity, a genuinely novel FDA-approved antidepressant. See its revenue and patent position.