Drug Interaction
RisksAn effect that occurs when two or more substances are taken together that wouldn't occur with either alone — ranging from harmless to dangerous depending on the combination.
Example: Ibogaine's cardiac risk gets substantially worse combined with other QT-prolonging drugs (see our ibogaine coverage), and ayahuasca's MAOI content can trigger serotonin syndrome with SSRIs or SNRIs — real risks, unlike the generally low risk of psilocybin or LSD combined with most antidepressants.
What is a drug interaction?
An effect that occurs when two or more substances are taken together that wouldn't occur with either alone — ranging from harmless to dangerous depending on the combination.
What are real dangerous psychedelic drug interactions?
Ibogaine's cardiac risk gets substantially worse combined with other QT-prolonging drugs, and ayahuasca's MAOI content can trigger serotonin syndrome with SSRIs or SNRIs — real risks, unlike the generally low risk of psilocybin or LSD combined with most antidepressants. See our ibogaine coverage.