DSM (Diagnostic and Statistical Manual)
ClinicalThe American Psychiatric Association's standard reference defining diagnostic criteria for mental health conditions — the rulebook nearly every clinical trial in this space uses to decide who qualifies as a participant.
Example: Nearly every psilocybin-for-depression trial uses the DSM-5-TR's major depressive disorder criteria — five or more specific symptoms present for at least two consecutive weeks — as the inclusion bar participants have to clear before they can enroll.
What is the DSM?
The American Psychiatric Association's standard reference defining diagnostic criteria for mental health conditions — the rulebook nearly every clinical trial in this space uses to decide who qualifies as a participant.
How does the DSM gate entry into a psilocybin depression trial?
Nearly every psilocybin-for-depression trial uses the DSM-5-TR's major depressive disorder criteria — five or more specific symptoms present for at least two consecutive weeks — as the inclusion bar participants have to clear before they can enroll.