Emotional Processing
OverlapThe capacity to access, feel, and work through difficult emotions and memories rather than avoiding or suppressing them — a mechanism many psychedelic-assisted therapies aim to unlock.
Example: In a treatment-resistant depression trial, psilocybin altered connectivity between the medial prefrontal cortex and amygdala the day after dosing, and the size of that connectivity change predicted patients' depression scores five weeks later.
What is emotional processing?
The capacity to access, feel, and work through difficult emotions and memories rather than avoiding or suppressing them — a mechanism many psychedelic-assisted therapies aim to unlock.
How does psilocybin change emotional-processing circuitry?
In a treatment-resistant depression trial, psilocybin altered connectivity between the medial prefrontal cortex and amygdala the day after dosing, and the size of that connectivity change predicted patients' depression scores five weeks later.