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Entactogen / Empathogen

Pharmacology

Class of substances that increase feelings of empathy, emotional openness, and connectedness (e.g., MDMA).

Example: MDMA is the field's clearest case — see our coverage of its VA and Pentagon trials for where the actual clinical evidence stands.

What is an entactogen?

A class of substances that increase feelings of empathy, emotional openness, and connectedness — MDMA is the clearest example.

Is MDMA the only entactogen studied clinically?

It's the field's clearest and most-studied case. See our coverage of its VA and Pentagon trials for where the actual clinical evidence stands.

Related Articles

Policy Aug 26, 2026

Psychedelics in Uniform: What the Military Did to Soldiers, and What the VA Is Now Asking of Veterans

The Army spent decades dosing enlisted men with psychedelics they weren't told they were taking. Eighty years later, the VA and Pentagon are running versions of the same experiment again — with consent forms, IRBs, and an executive order behind them.

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