Entourage Effect
CompoundA theory, borrowed from cannabis research, that a plant's full mix of compounds can produce effects beyond what any single isolated molecule does alone.
Example: In one mouse study, whole Psilocybe argentipes mushroom extract reduced anxiety-like behavior more effectively than pure psilocybin alone — a hint that minor alkaloids like aeruginascin (see entry above) may matter more than their trace concentrations suggest.
What is the entourage effect?
A theory, borrowed from cannabis research, that a plant's full mix of compounds can produce effects beyond what any single isolated molecule does alone.
Is there evidence for an entourage effect in mushrooms?
Some — in one mouse study, whole Psilocybe argentipes mushroom extract reduced anxiety-like behavior more effectively than pure psilocybin alone, a hint that minor alkaloids like aeruginascin may matter more than their trace concentrations suggest.