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Equipoise (Clinical)
ClinicalA state of genuine scientific uncertainty about which of two treatments is better — the ethical prerequisite for randomizing patients to one or the other in a trial. Loses force fast once a drug's effects are dramatic and obvious to the patient, which is part of psychedelic research's broader blinding problem (see Double-Blind Study above).
What is clinical equipoise?
A state of genuine scientific uncertainty about which of two treatments is better — the ethical prerequisite for randomizing patients to one or the other in a trial.
Why is equipoise hard to maintain in psychedelic trials?
It loses force fast once a drug's effects are dramatic and obvious to the patient, which is part of psychedelic research's broader blinding problem. See our Double-Blind Study entry.