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A synthetic opioid roughly 50 times more potent than heroin, responsible for the majority of US overdose deaths.

Example: Drug-checking services have found fentanyl contaminating samples across multiple drug classes, including psychedelics like 2C-B, mescaline, and DMT — though the data shows psychedelics make up a small share of what gets tested, so a compound being a "psychedelic" offers no inherent protection from a contaminated supply.