Salience Network
NeuroscienceA brain network, anchored in the insula and anterior cingulate cortex, that filters which internal and external signals are important enough to command attention.
Example: In a randomized, placebo-controlled trial of 24 healthy adults, psilocybin decreased connectivity within the salience network and reduced top-down connectivity from resting-state networks to the amygdala — changes the researchers linked to psilocybin's altered sense of emotional meaning during the session.
What is the salience network?
A brain network, anchored in the insula and anterior cingulate cortex, that filters which internal and external signals are important enough to command attention.
How does psilocybin affect the salience network?
In a randomized, placebo-controlled trial of 24 healthy adults, psilocybin decreased connectivity within the salience network and reduced top-down connectivity from resting-state networks to the amygdala — changes researchers linked to psilocybin's altered sense of emotional meaning during the session.