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Jan 5, 2026 Neuroscience
5-MeO-DMT Puts Mice in a State That Looks Awake and Asleep at the Same Time
Oxford researchers gave mice 5-MeO-DMT and found something odd: the animals stayed behaviorally active, with dilated pupils and normal muscle tone, while their brains showed the slow-wave activity you'd expect from sleep — a dissociated state that doesn't fit neatly into "awake" or "asleep." It's mice, not the felt experience of a Bufo session, but it's a real physiological signature for what the compound does to a brain in real time.
Read at Communications Biology