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May 2021 Randomized Controlled Trial
Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder — A Randomized Clinical Trial
Davis AK, Barrett FS, May DG, et al. — Johns Hopkins Center for Psychedelic and Consciousness Research
Published in JAMA Psychiatry
Psilocybin Depression
27 participants with major depressive disorder were randomized to immediate vs. delayed (waitlist) psilocybin-assisted therapy. 71% showed a clinically significant response at both week 1 and week 4; effects were rapid and sustained for at least a month.
Read the Full Paper at JAMA Psychiatry