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MDMA-Assisted Therapy for Severe PTSD: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study

Mitchell JM, Bogenschutz M, Lilienstein A, et al. — University of California, San Francisco / MAPS

Published in Nature Medicine

90 participants with severe PTSD were randomized to MDMA-assisted therapy or placebo with therapy. CAPS-5 scores dropped by 24.4 points in the MDMA group vs. 13.9 in placebo, with no reported adverse events of abuse potential, suicidality, or QT prolongation.

Read the Full Paper at Nature Medicine