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Mystical Experiences Occasioned by the Hallucinogen Psilocybin Lead to Increases in the Personality Domain of Openness

MacLean KA, Johnson MW, Griffiths RR — Johns Hopkins University School of Medicine

Published in Journal of Psychopharmacology

The first study to show measurable personality change in healthy adults following a single, discrete event. Participants who had a mystical-type experience during a high-dose psilocybin session showed significantly higher Openness scores more than a year later — personality traits are normally considered stable in adulthood, which is what made this result notable.

Read the Full Paper at Journal of Psychopharmacology