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Dec 2016 Randomized Controlled Trial

Psilocybin Produces Substantial and Sustained Decreases in Depression and Anxiety in Patients With Life-Threatening Cancer: A Randomized Double-Blind Trial

Griffiths RR, Johnson MW, Carducci MA, et al. — Johns Hopkins University School of Medicine

Published in Journal of Psychopharmacology

Psilocybin DepressionAnxietyCancer-Related Distress

51 cancer patients with life-threatening diagnoses received a high dose (22 or 30 mg/70kg) and a low dose of psilocybin in a crossover design. High-dose sessions produced large decreases in depression and anxiety; at 6-month follow-up, roughly 80% still showed clinically significant improvement.

Read the Full Paper at Journal of Psychopharmacology