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Jun 2018 Randomized Controlled Trial
Rapid Antidepressant Effects of the Psychedelic Ayahuasca in Treatment-Resistant Depression — A Randomized Placebo-Controlled Trial
Palhano-Fontes F, Barreto D, Onias H, et al. — Federal University of Rio Grande do Norte, Brazil
Published in Psychological Medicine
29 patients with treatment-resistant depression received a single dose of ayahuasca or placebo. 64% of the ayahuasca group responded by day 7 vs. 27% on placebo; remission trended toward significance (36% vs. 7%, p=0.054). A real placebo response showed up too, but ayahuasca's effect was larger and held longer.
Read the Full Paper at Psychological Medicine