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Fadiman Protocol

Psychedelic

Microdosing schedule of one dose day followed by two rest days, repeated in 4–8 week cycles.

Example: Named for psychologist James Fadiman, the design deliberately spaces doses to avoid tolerance buildup — a real, specific protocol, though it's worth remembering our Microdosing entry covers why the controlled-trial evidence for microdosing itself still lags the enthusiasm around protocols like this one.

What is the Fadiman Protocol?

A microdosing schedule of one dose day followed by two rest days, repeated in 4-8 week cycles, named for psychologist James Fadiman.

Does the Fadiman Protocol have strong clinical evidence behind it?

The design deliberately spaces doses to avoid tolerance buildup, but the controlled-trial evidence for microdosing itself still lags the enthusiasm around specific protocols like this one. See our Microdosing entry.